- 规格参数
- 产品介绍
- 售后保障
- 商品评价
- 仓储包装
- 常见问题
碧云天 Recombinant Huma... 当商品进行补货时,我们将以短信、邮件的形式通知您,最多发送一次,不会对您造成干扰。 |
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产品编号 | 产品名称 | 产品包装 | 产品价格 |
P5223-10μg | Recombinant Human IL-21 | 10μg | 1671.00元 |
P5223-100μg | Recombinant Human IL-21 | 100μg | 10650.00元 |
P5223-1mg | Recombinant Human IL-21 | 1mg | 34065.00元 |
Species | Gene ID | Accession | Source | Length | MW | Tag |
Human | 59067 | Q9HBE4 | E. coli | 133aa | 15.4kDa | - |
About this protein | |
Name | Recombinant Human IL-21 (Recombinant Human Interleukin-21; rHuIL-21);重组人白细胞介素21 |
Synonyms | CVID11; IL-21; Za11 |
Purity | >97% by SDS-PAGE and HPLC analyses. |
Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by by a cell proliferation assay using human N1186 T cells is less than 20ng/ml, corresponding to a specific activity of >5.0×104IU/mg. |
Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4. |
Endotoxin | Less than 1EU/μg of rHuIL-21 as determined by LAL method. |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
Category | Cytokine |
Background | Human IL-21 is encoded by IL-21 gene located on Chr. 4. It is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation and can regulating immune system cells, for instance cytotoxin T cells and natural killer cells. Additionally, it can induce target cells division or proliferation. IL-21 elicits its effect through binding to IL-21R, which also contains the gamma chain found in other cytokine receptors such as IL-2, IL-4, IL-7, IL-9 and IL-15. IL-21/IL-21R interaction triggers a cascade of events which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. IL-21 shows having much relation with clinical illnesses, including cancer immunotherapy, viral infections and allergies. |
Amino Acid Sequence | QGQDRHMIRM RQLIDIVDQL KNYVNDLVPE FLPAPEDVET NCEWSAFSCF QKAQLKSANT GNNERIINVS IKKLKRKPPS TNAGRRQKHR LTCPSCDSYE KKPPKEFLER FKSLLQKMIH QHLSSRTHGS EDS |
包装清单:
产品编号 | 产品名称 | 包装 |
P5223-2μg | Recombinant Human IL-21 | 2μg |
P5223-10μg | Recombinant Human IL-21 | 10μg |
P5223-100μg | Recombinant Human IL-21 | 100μg |
P5223-1mg | Recombinant Human IL-21 | 1mg |
- | 说明书 | 1份 |
保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
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